Tuneable pH-regulated supramolecular copolymerisation by mixing mismatched dendritic peptide comonomers†‡
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چکیده
Charged phenylalanine-rich dendritic peptides form highly stable and pH-switchable rod-like supramolecular copolymers, when co-assembled with a matching oppositely charged dendritic comonomer. Here, Besenius and coworkers demonstrate that by mismatching a strong with a weak -sheet encoded comonomer, both the stability and the pH-triggered disassembly of the copolymers shifts from pH 4.2 to biologically relevant pH 5.8.
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تاریخ انتشار 2015